ProMIS Neurosciences Inc. (PMN:TSX; ARFXF:OTCQB) and its partner, BC Neuroimmunology (BCNI), will collaborate to develop highly sensitive and specific assays for use in accurately screening for and diagnosing Alzheimer's disease, ProMIS announced in a news release.
"We intend to help address this very important unmet need by capitalizing on our existing portfolio of antibodies and antigens and applying these existing assets to BCNI's outstanding expertise in the development of high performance diagnostic tests," ProMIS Executive Chairman Eugene Williams said in the release.
The two companies state they intend to use surface plasmon resonance (SPR) technology, with which they both have extensive experience, to develop sensitive blood-based Alzheimer's disease diagnostic tests cheaply and quickly. ProMIS has a "unique, core technology to predict novel targets on the molecular surface of complex proteins."
Because significant advances have been made in the throughput and stability of SPR technology, it could replace ELISA, or enzyme-linked immunosorbent assay, as the new cost-effective standard, the release stated.
ProMIS and BCNI also are working on developing an SPR-based antibody assay designed to achieve 100% sensitivity and 99.9% specificity for the virus that causes COVID-19.
"At BCNI, we are developing high-throughput SPR tests in conjunction with ProMIS whose unique peptide antigens are anticipated to be a critical component for development and commercialization of top quality assays targeting infectious disease, such as COVID-19, and neurodegenerative disease, such as Alzheimer's," BCNI CEO Dr. Hans Frykman said in the release.
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