Get the Latest Investment Ideas Delivered Straight to Your Inbox. Subscribe

TICKERS: AXON

Clinical Movement Expected in 2019 on Pharma Firm's 'Gene Therapy Promise'
Research Report

Share on Stocktwits

Source:

A number of data readouts are expected in the coming months, which could derisk and accelerate development programs, according to an H.C. Wainwright & Co. report.

In a Feb. 8 research note, H.C. Wainwright analyst Andrew Fein wrote that Axovant Sciences Ltd. (AXON:NYSE) will likely clinically advance its gene therapy pipeline quickly.

Evidence of this, noted Fein, is the "strong execution" the company displayed over the past year, bolstering the pipeline, speeding up development timelines and recruiting top gene therapy experts. These efforts have been part of the company rebuild and shift into the gene therapy space.

Second, Fein highlighted, a steady flow of trial results is expected over the next few months. Specifically, initial data from AXO-Lenti-PD are anticipated in Q1/19, initial results from AXO-Lenti-PD are expected in March 2019 and initial findings from AXO-AAV-GM1 should read out in H2/19. These data releases can derisk those clinical programs.

"AXO-Lenti-PD is moving forward," Fein indicated, and could do so on an accelerated development path by leveraging the data set from ProSavin, a predecessor gene therapy product. "For AXO-Lenti-PD, we believe that the scientific rationale is strong by delivering aromatic L-amino acid decarboxylase into the putamen of patients with Parkinson's disease, and this approach has been supported by the clinical data from both ProSavin and VY-AADC thus far."

Further, Fein added, the FDA indicated that Axovant may consider ProSavin results as part of one AXO-Lenti-PD development program, and it agreed with the company's manufacturing and quality control plans.

As for Axovant's financial standing, it had $84.9 million in cash and cash equivalents at year-end 2018.

H.C. Wainwright has a Buy rating and a $7 per share price target on Axovant, whose current share price is around $1.24.

[NLINSERT]

Disclosure:
1) Doresa Banning compiled this article for Streetwise Reports LLC and provides services to Streetwise Reports as an independent contractor. She or members of her household own securities of the following companies mentioned in the article: None. She or members of her household are paid by the following companies mentioned in this article: None.
2) The following companies mentioned in this article are billboard sponsors of Streetwise Reports: None. Click here for important disclosures about sponsor fees.
3) Comments and opinions expressed are those of the specific experts and not of Streetwise Reports or its officers. The information provided above is for informational purposes only and is not a recommendation to buy or sell any security.
4) The article does not constitute investment advice. Each reader is encouraged to consult with his or her individual financial professional and any action a reader takes as a result of information presented here is his or her own responsibility. By opening this page, each reader accepts and agrees to Streetwise Reports' terms of use and full legal disclaimer. This article is not a solicitation for investment. Streetwise Reports does not render general or specific investment advice and the information on Streetwise Reports should not be considered a recommendation to buy or sell any security. Streetwise Reports does not endorse or recommend the business, products, services or securities of any company mentioned on Streetwise Reports.
5) From time to time, Streetwise Reports LLC and its directors, officers, employees or members of their families, as well as persons interviewed for articles and interviews on the site, may have a long or short position in securities mentioned. Directors, officers, employees or members of their immediate families are prohibited from making purchases and/or sales of those securities in the open market or otherwise from the time of the interview or the decision to write an article until three business days after the publication of the interview or article. The foregoing prohibition does not apply to articles that in substance only restate previously published company releases.

Disclosures from H.C. Wainwright & Co., Axovant Sciences Ltd., Earnings Update, February 8, 2019

I, Andrew S. Fein, Li Wang Watsek and Alicia Yin, Ph.D., certify that 1) all of the views expressed in this report accurately reflect my personal views about any and all subject securities or issuers discussed; and 2) no part of my compensation was, is, or will be directly or indirectly related to the specific recommendation or views expressed in this research report; and 3) neither myself nor any members of my household is an officer, director or advisory board member of these companies.

Investment Banking Services include, but are not limited to, acting as a manager/co-manager in the underwriting or placement of securities, acting as financial advisor, and/or providing corporate finance or capital markets-related services to a company or one of its affiliates or subsidiaries within the past 12 months.

None of the research analysts or the research analyst's household has a financial interest in the securities of Axovant Sciences Ltd., Neurocrine Biosciences, Inc. and Voyager Therapeutics, Inc. (including, without limitation, any option, right, warrant, future, long or short position).

As of January 31, 2019 neither the Firm nor its affiliates beneficially own 1% or more of any class of common equity securities of Axovant Sciences Ltd., Neurocrine Biosciences, Inc. and Voyager Therapeutics, Inc.

Neither the research analyst nor the Firm has any material conflict of interest in of which the research analyst knows or has reason to know at the time of publication of this research report.

The research analyst principally responsible for preparation of the report does not receive compensation that is based upon any specific investment banking services or transaction but is compensated based on factors including total revenue and profitability of the Firm, a substantial portion of which is derived from investment banking services.

The Firm or its affiliates did not receive compensation from Neurocrine Biosciences, Inc. and Voyager Therapeutics, Inc. for investment banking services within twelve months before, but will seek compensation from the companies mentioned in this report for investment banking services within three months following publication of the research report.

The Firm or its affiliates did receive compensation from Axovant Sciences Ltd. for investment banking services within twelve months before, and will seek compensation from the companies mentioned in this report for investment banking services within three months following publication of the research report.

H.C. Wainwright & Co., LLC managed or co-managed a public offering of securities for Axovant Sciences Ltd. during the past 12 months.

The Firm does not make a market in Axovant Sciences Ltd., Neurocrine Biosciences, Inc. and Voyager Therapeutics, Inc. as of the date of this research report.





Want to read more about Biotechnology / Pharmaceuticals investment ideas?
Get Our Streetwise Reports Newsletter Free and be the first to know!

A valid email address is required to subscribe